ParkinsonCanadaV1, Main, Exploration, bibRecord, 002417

Aging hippocampus and amygdala

Identifieur interne : 002417 ( Main/Exploration ); précédent : 002416; suivant : 002418

Aging hippocampus and amygdala

Auteurs : Nikolai V. Malykhin [Canada] ; Thomas P. Bouchard [Canada] ; Richard Camicioli [Canada] ; Nicholas J. Coupland [Canada]

Source :

Neuroreport : (Oxford) [ 0959-4965 ] ; 2008.

RBID : Pascal:08-0217272

Descripteurs français

Pascal (Inist)
- Sénescence, Hippocampe, Amygdale, Noyau amygdalien, Encéphale, Imagerie RMN, Lobe temporal, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Amygdala, Amygdaloid nucleus, Encephalon, Hippocampus, Human, Nuclear magnetic resonance imaging, Senescence, Temporal lobe.

Abstract

Earlier studies suggest that the anterior hippocampus may show resilience to age-associated volume loss. This study compared high-resolution magnetic resonance images obtained from younger (n=28; age range: 22-50 years) and older (n=39; age range: 65-84 years) healthy right-handed individuals to determine whether age-related volume changes varied between the hippocampal head, body and tail. Volumetric reductions were progressively more severe from hippocampal head to tail. Amygdala volume differences were intermediate in size. Although limited by the cross-sectional design, these data suggest that hippocampal subregions show a gradient of volume reduction in healthy aging that contrasts with the preferential reduction of anterior hippocampal volumes in Alzheimer's and Parkinson's diseases.

Affiliations:

Canada

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000655
to stream PascalFrancis, to step Curation: 000655
to stream PascalFrancis, to step Checkpoint: 000568
to stream Main, to step Merge: 002629
to stream Main, to step Curation: 002417

Le document en format XML

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<term>Nuclear magnetic resonance imaging</term>
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<term>Imagerie RMN</term>
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<front><div type="abstract" xml:lang="en">Earlier studies suggest that the anterior hippocampus may show resilience to age-associated volume loss. This study compared high-resolution magnetic resonance images obtained from younger (n=28; age range: 22-50 years) and older (n=39; age range: 65-84 years) healthy right-handed individuals to determine whether age-related volume changes varied between the hippocampal head, body and tail. Volumetric reductions were progressively more severe from hippocampal head to tail. Amygdala volume differences were intermediate in size. Although limited by the cross-sectional design, these data suggest that hippocampal subregions show a gradient of volume reduction in healthy aging that contrasts with the preferential reduction of anterior hippocampal volumes in Alzheimer's and Parkinson's diseases.</div>
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	La maladie de Parkinson au Canada (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

La maladie de Parkinson au Canada (serveur d'exploration)

Aging hippocampus and amygdala

Aging hippocampus and amygdala

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri